Many gastrointestinal diseases have a known causative mutation and require chronic management. These include cancer syndromes such as Hereditary diffuse gastric cancer, Lynch syndrome, Familial adenomatous polyposis, Hereditary pancreatitis, Hemochromatosis etc. Patients with strong family history of colon cancer, cirrhosis/liver cancer, uterine cancer, ampullary cancer, thyroid cancer, breast cancer, ovarian cancer or melanoma should be evaluated for Genetic cancer syndromes.

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